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Anapolin (Oxymetholone) also known as Anadrol is probably by far the most popular oral steroid used by athletes today for bulking. It gained its reputation for being an extremely powerful and cheap steroid as mentioned in the original underground steroid handbook written by Dan Duchaine. He presented it as a cheaper alternative to Methandrostanalone (Dianabol).
Anapolin is a Dihydrotestosterone (DHT)-derivative with the addition of a 2-hydroxymethylene group.
It is the only DHT derived steroid that is used to bulk up. Others such as Masteron (Drostanalone propionate), Proviron (Mesterolone acetate), Winstrol (Stanazolol), Anavar (Oxandrolone) and Primobolin (Methenolone acetate) as all used for cutting making Anapolin a very unique DHT-derivative compound.
It is a 17-Alpha-Alkylated steroid as it has been altered at the 17th carbon position to survive oral ingestion and passing through the liver. Anapolin also doesn’t bind well to the androgen receptor. Anapolin does not convert to estrogen, but estrogen related issues may arise due to its progestational activity. It is advised to use an estrogen antagonist when using Anapolin. It’s been used to successfully combat AIDS and other wasting diseases.
Water retention: Yes
High blood pressure: Yes, extremely
Liver toxic: Highly toxic
Aromatization: No, but high progestational activity
may cause estrogen related side effects
DHT Conversion: Yes, as it is a DHT derivative
Decreased HPTA function: Yes, to the extreme